Pokémon Puzzle Challenge offers plenty of modes for a single Game Boy Color cartridge. Here is each one, from Challenge mode against the Johto Gym Leaders to Clear mode.

Challenge Mode

The main mode: take on the eight Johto Gym Leaders, from Falkner to Clair, then the Elite Four. Victories unlock new playable Pokémon.

The Other Modes

ModeHow it works
MarathonThe stack rises faster and faster; survive as long as possible.
Time TrialLike Marathon, but against the clock: score as many points as possible.
LineClear blocks fast enough to bring the stack below a line.
PuzzleIncreasingly difficult puzzles with a limited number of moves.
ClearEmpty the screen of blocks that keep falling from the top.
Two PlayersA duel using the Game Link Cable.
TutorialLearn the rules and techniques.

The Rules

You swap two horizontally adjacent blocks to line up at least three blocks of the same color. Combos, which clear more than three blocks at once, and chains, which are cascading clears, send garbage blocks to your opponent. The details are on our Puzzle League rules and tips page, which also applies to this game.